PDBsum entry 7e17

Cell invasion

PDB id: 7e17

Contents

Protein chains

225 a.a.

232 a.a.

Ligands

NAG ×6

PDB id:

7e17

Name:

Cell invasion

Title:

Structure of dimeric upar

Structure:

Urokinase plasminogen activator surface receptor. Chain: a, b. Synonym: upar,monocyte activation antigen mo3. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: plaur, mo3, upar. Expressed in: drosophila melanogaster. Expression_system_taxid: 7227. Expression_system_variant: s2 cells.

Resolution:

2.96Å R-factor: 0.251 R-free: 0.299

Authors:

Y.Cai,M.Huang

Key ref:

S.Yu et al. (2022). Crystal structure and cellular functions of upar dime. Nat commun, 13, 1665.

Date:

01-Feb-21 Release date: 22-Dec-21

Protein chain

Q03405  (UPAR_HUMAN) -  Urokinase plasminogen activator surface receptor from Homo sapiens

Seq: 335 a.a.

Struc: 225 a.a.*

Protein chain

Q03405  (UPAR_HUMAN) -  Urokinase plasminogen activator surface receptor from Homo sapiens

Seq: 335 a.a.

Struc: 232 a.a.*

* PDB and UniProt seqs differ at 2 residue positions (black crosses)