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PDBsum entry 7cvh
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PDB id:
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Hydrolase
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Title:
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Human fructose-1,6-bisphosphatase 1 in complex with geranylgeranyl diphosphate
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Structure:
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Fructose-1,6-bisphosphatase 1. Chain: a, c, b, d. Synonym: fbpase 1,d-fructose-1,6-bisphosphate 1-phosphohydrolase 1, liver fbpase. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: fbp1, fbp. Expressed in: escherichia coli. Expression_system_taxid: 562
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Resolution:
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2.09Å
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R-factor:
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0.179
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R-free:
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0.218
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Authors:
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Y.Chen,J.Zhang,C.Li,Y.Cao
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Key ref:
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Y.Chen
et al.
The structural basis for ggpp activation on the enzym activities fbp1.
To be published,
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Date:
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26-Aug-20
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Release date:
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08-Sep-21
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PROCHECK
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Headers
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References
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P09467
(F16P1_HUMAN) -
Fructose-1,6-bisphosphatase 1 from Homo sapiens
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Seq:
Struc:
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338 a.a.
319 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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Enzyme class:
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E.C.3.1.3.11
- fructose-bisphosphatase.
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Pathway:
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Pentose Phosphate Pathway (later stages)
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Reaction:
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beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-phosphate + phosphate
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beta-D-fructose 1,6-bisphosphate
Bound ligand (Het Group name = )
corresponds exactly
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+
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H2O
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=
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beta-D-fructose 6-phosphate
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+
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phosphate
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
