PDBsum entry 7ced

Oxidoreductase

PDB id: 7ced

Contents

Protein chains

(+ 2 more) 573 a.a.

(+ 2 more) 71 a.a.

Waters ×4709

PDB id:

7ced

Name:

Oxidoreductase

Title:

Apo-methanol dehydrogenase (mdh) from methylococcus capsulatus (bath)

Structure:

Methanol dehydrogenase protein, large subunit. Chain: a, b, c, d, g, h, m, n. Methanol dehydrogenase [cytochrome c] subunit 2. Chain: e, f, i, j, k, l, o, p. Synonym: mdh small subunit beta,mdh-associated peptide,medh. Engineered: yes

Source:

Methylococcus capsulatus (strain atcc 33009 / ncimb 11132 / bath). Organism_taxid: 243233. Strain: atcc 33009 / ncimb 11132 / bath. Gene: mxai, mca0782. Expressed in: methylococcus capsulatus str. Bath. Expression_system_taxid: 243233

Resolution:

1.90Å R-factor: 0.140 R-free: 0.180

Authors:

P.Chuankhayan,S.I.Chan,P.K.R.Nareddy,I.K.Tsai,Y.F.Tsai,K.H.-C.Chen, S.S.-F.Yu,C.J.Chen

Key ref:

S.I.Chan et al. (2021). Mechanism of pyrroloquinoline quinone-Dependent hydri transfer chemistry from spectroscopic and high-Resolu X-Ray structural studies of the methanol dehydrogenas methylococcus capsulatus (bath).. J am chem soc, 143, 3359. PubMed id: 33629832

Date:

22-Jun-20 Release date: 30-Jun-21

Protein chains

Q60AR6  (Q60AR6_METCA) -  Methanol dehydrogenase protein, large subunit from Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)

Seq: 601 a.a.

Struc: 573 a.a.

Protein chains

Q60AR3  (Q60AR3_METCA) -  Methanol dehydrogenase [cytochrome c] subunit 2 from Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)

Seq: 94 a.a.

Struc: 71 a.a.

Enzyme reactions

• Enzyme class: Chains E, F, I, J, K, L, O, P: E.C.1.1.2.7 - methanol dehydrogenase (cytochrome c).
• Reaction: 2 Fe(III)-[cytochrome cL] + a primary alcohol = 2 Fe(II)-[cytochrome cL] + an aldehyde + 2 H⁺
• Cofactor: Pyrroloquinoline quinone

Molecule diagrams generated from .mol files obtained from the KEGG ftp site