PDBsum entry 7ccc

Structural protein

PDB id: 7ccc

Contents

Protein chains

357 a.a.

342 a.a.

269 a.a.

248 a.a.

Ligands

ADP ×2

Metals

_CA ×2

Waters ×54

PDB id:

7ccc

Name:

Structural protein

Title:

The structure of the actin filament uncapping complex mediated by twinfilin

Structure:

Actin, alpha skeletal muscle. Chain: a, e. Synonym: alpha-actin-1. Twinfilin-1. Chain: b. Synonym: protein a6,protein tyrosine kinase 9. Engineered: yes. F-actin-capping protein subunit alpha. Chain: c.

Source:

Oryctolagus cuniculus. Rabbit. Organism_taxid: 9986. Homo sapiens. Human. Organism_taxid: 9606. Gene: twf1, ptk9. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

3.20Å R-factor: 0.192 R-free: 0.238

Authors:

R.C.Robinson,D.M.Mwangangi

Date:

16-Jun-20 Release date: 03-Feb-21

Protein chains

P68135  (ACTS_RABIT) -  Actin, alpha skeletal muscle from Oryctolagus cuniculus

Seq: 377 a.a.

Struc: 357 a.a.*

Protein chain

Q12792  (TWF1_HUMAN) -  Twinfilin-1 from Homo sapiens

Seq: 350 a.a.

Struc: 342 a.a.

Protein chain

P47753  (CAZA1_MOUSE) -  F-actin-capping protein subunit alpha-1 from Mus musculus

Seq: 286 a.a.

Struc: 269 a.a.

Protein chain

Q923G3  (Q923G3_MOUSE) -  F-actin-capping protein subunit beta from Mus musculus

Seq: 272 a.a.

Struc: 248 a.a.

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: Chains A, E: E.C.3.6.4.- - ?????