PDBsum entry 7c7c

Chaperone

PDB id: 7c7c

Contents

Protein chain

429 a.a.

Ligands

FK0

PDB id:

7c7c

Name:

Chaperone

Title:

Crystal structure of human trap1 with sjt104

Structure:

Heat shock protein 75 kda, mitochondrial. Chain: a. Synonym: hsp 75,tnfr-associated protein 1,tumor necrosis factor type 1 receptor-associated protein,trap-1. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: trap1, hsp75. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

Resolution:

3.00Å R-factor: 0.236 R-free: 0.303

Authors:

D.Kim,S.Yang,N.G.Yoon,E.Park,S.Y.Kim,B.H.Kang,C.Lee,S.Kang

Key ref:

S.Yang et al. Design and synthesis of trap1 selective inhibitors: interacting with asn171 residue in trap1 to in-Crease paralog selectivity. To be published, . PubMed id: 34267888

Date:

24-May-20 Release date: 26-May-21

Protein chain

Q12931  (TRAP1_HUMAN) -  Heat shock protein 75 kDa, mitochondrial from Homo sapiens

Seq: 704 a.a.

Struc: 429 a.a.