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PDBsum entry 7bcs
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Membrane protein
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PDB id
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7bcs
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PDB id:
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| Name: |
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Membrane protein
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Title:
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Asct2 in the presence of the inhibitor lc-bpe (position "down") in the outward-open conformation.
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Structure:
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Neutral amino acid transporter b(0). Chain: a, b, c. Synonym: atb(0),baboon m7 virus receptor,rd114/simian type d retrovirus receptor,sodium-dependent neutral amino acid transporter type 2,solute carrier family 1 member 5. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: slc1a5, asct2, m7v1, rdr, rdrc. Expressed in: komagataella pastoris. Expression_system_taxid: 4922
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Authors:
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R.A.Garibsingh,E.Ndaru,A.A.Garaeva,Y.Shi,L.Zielewicz,M.Bonomi, D.J.Slotboom,C.Paulino,C.Grewer,A.Schlessinger
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Key ref:
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R.A.Garibsingh
et al.
(2021).
Rational design of asct2 inhibitors using an integrat experimental-Computational approach..
Proc natl acad sci usa,
118,
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PubMed id:
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Date:
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21-Dec-20
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Release date:
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22-Sep-21
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PROCHECK
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Headers
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References
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Q15758
(AAAT_HUMAN) -
Neutral amino acid transporter B(0) from Homo sapiens
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Seq:
Struc:
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541 a.a.
442 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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Links
