PDBsum entry 7ba4

Cytosolic protein

PDB id: 7ba4

Contents

Protein chains

377 a.a.

358 a.a.

Ligands

PLP ×4

Waters ×1177

PDB id:

7ba4

Name:

Cytosolic protein

Title:

Structure of cystathionine gamma-lyase from pseudomonas aeruginosa

Structure:

Cystathionine gamma-lyase. Chain: a, b, c, d. Synonym: cystathionine gamma-synthase. Engineered: yes

Source:

Pseudomonas aeruginosa. Organism_taxid: 287. Gene: cgu42_31115, ecc04_012645, fc629_02215, gnq48_07915, ipc582_10875. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

2.00Å R-factor: 0.162 R-free: 0.205

Authors:

C.Fernandez-Rodriguez,I.Oyenarte,I.Gonzalez-Recio,T.Majtan,A.Astegno, L.A.Martinez-Cruz

Key ref:

C.Fernandez-Rodriguez et al. Structure of cystathionine gamma-Lyase from pseudomon aeruginosa. To be published, .

Date:

15-Dec-20 Release date: 29-Sep-21

Protein chains

A0A509J8D5  (A0A509J8D5_PSEAI) -  Cystathionine gamma-lyase from Pseudomonas aeruginosa

Seq: 394 a.a.

Struc: 377 a.a.

Protein chain

A0A509J8D5  (A0A509J8D5_PSEAI) -  Cystathionine gamma-lyase from Pseudomonas aeruginosa

Seq: 394 a.a.

Struc: 358 a.a.

Enzyme reactions

• Enzyme class: Chains A, B, C, D: E.C.2.5.1.48 - cystathionine gamma-synthase.
• Reaction: O-succinyl-L-homoserine + L-cysteine = L,L-cystathionine + succinate + H⁺
• Cofactor: Pyridoxal 5'-phosphate

Pyridoxal 5'-phosphate (Bound ligand (Het Group name = PLP) matches with 93.75% similarity)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site