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PDBsum entry 7ahh
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protein ligands Protein-protein interface(s) links
Membrane protein PDB id
7ahh

 

 

 

 

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Contents
Protein chains
526 a.a.
272 a.a.
382 a.a.
Ligands
BET
ANP ×2
2BA
PDB id:
7ahh
Name: Membrane protein
Title: Opua inhibited inward-facing, sbd docked
Structure: Abc transporter permease subunit. Chain: a, b. Synonym: abc-type proline/glycine betaine transport system permease component,glycine betaine abc transport system permease and betaine- binding protein. Engineered: yes. Abc-type proline/glycine betaine transport system atpase component. Chain: c, d.
Source: Lactococcus lactis subsp. Lactis. Organism_taxid: 1360. Gene: fez45_03205, fib48_03540, gji88_00475, gji90_00975, ll275_1486, n42_0725. Expressed in: lactococcus lactis subsp. Lactis. Expression_system_taxid: 1360. Gene: fez45_03200, gji88_00480, gji90_00980, kf282_2364, ll275_1487, m20_1239, n42_0726. Expression_system_taxid: 1360
Authors: H.R.Sikkema,J.Rheinberger,C.Paulino,B.Poolman
Key ref: h.r.sikkema et al. (2020). Gating by ionic strength and safety check by cyclic-di-AMP in the ABC transporter OpuA. Sci Adv, 6, . PubMed id: 33208376
Date:
24-Sep-20     Release date:   25-Nov-20    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
A0A0V8ETW8  (A0A0V8ETW8_LACLL) -  ABC transporter permease subunit from Lactococcus lactis subsp. lactis
Seq:
Struc: 		 
Seq:
Struc: 		573 a.a.
526 a.a.
Protein chain
Pfam   ArchSchema ?
A0A0V8ETW8  (A0A0V8ETW8_LACLL) -  ABC transporter permease subunit from Lactococcus lactis subsp. lactis
Seq:
Struc: 		 
Seq:
Struc: 		573 a.a.
272 a.a.
Protein chains
Pfam   ArchSchema ?
Q9KIF7  (OPUAA_LACLA) -  Glycine betaine transport ATP-binding protein OpuAA from Lactococcus lactis subsp. lactis (strain IL1403)
Seq:
Struc: 		408 a.a.
382 a.a.
Key:    PfamA domain  Secondary structure

 Enzyme reactions 
   Enzyme class: Chains C, D: E.C.7.6.2.9  - ABC-type quaternary amine transporter.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: a quaternary ammonium(out) + ATP + H2O = a quaternary ammonium(in) + ADP + phosphate + H+
quaternary ammonium(out)
 + ATP
 + H2O
 = quaternary ammonium(in)
 +
ADP
Bound ligand (Het Group name = ANP)
matches with 81.25% similarity 		+ phosphate
 + H(+)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 

 
    reference    
 
 
Sci Adv 6: (2020)
PubMed id: 33208376  
 
 
Gating by ionic strength and safety check by cyclic-di-AMP in the ABC transporter OpuA.
h.r.sikkema, m.van den noort, j.rheinberger, m.de boer, s.t.krepel, g.k.schuurman-wolters, p.paulino, b.poolman.
 
  ABSTRACT  
 
No abstract given.

 

 

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