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PDBsum entry 7a1f
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PDB id:
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Lyase
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Title:
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Crystal structure of human 5' exonuclease appollo in complex with 5'damp
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Structure:
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5' exonuclease apollo. Chain: a, l. Synonym: DNA cross-link repair 1b protein,snm1 homolog b,hsnm1b. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: dclre1b, snm1b. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108
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Resolution:
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1.80Å
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R-factor:
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0.180
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R-free:
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0.223
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Authors:
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J.A.Newman,H.T.Baddock,S.M.M.Mukhopadhyay,N.A.Burgess-Brown,F.Von Delft,C.H.Arrowshmith,A.Edwards,C.Bountra,O.Gileadi
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Key ref:
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J.A.Newman
et al.
Crystal structure of human 5' Exonuclease appollo in with 5'Damp.
To be published,
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PubMed id:
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Date:
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12-Aug-20
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Release date:
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20-Jan-21
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PROCHECK
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Headers
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References
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Q9H816
(DCR1B_HUMAN) -
5' exonuclease Apollo from Homo sapiens
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Seq:
Struc:
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532 a.a.
329 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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*
PDB and UniProt seqs differ
at 1 residue position (black
cross)
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Enzyme class 2:
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E.C.3.1.-.-
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Enzyme class 3:
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E.C.3.5.2.6
- beta-lactamase.
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Pathway:
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Reaction:
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a beta-lactam + H2O = a substituted beta-amino acid
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Cofactor:
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Zn(2+)
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Note, where more than one E.C. class is given (as above), each may
correspond to a different protein domain or, in the case of polyprotein
precursors, to a different mature protein.
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Links
