PDBsum entry 6zph

Motor protein

PDB id: 6zph

Contents

Protein chains

457 a.a.

315 a.a.

Ligands

ADP

Metals

_MG

PDB id:

6zph

Name:

Motor protein

Title:

Kinesin binding protein complexed with kif15 motor domain

Structure:

Kif-binding protein. Chain: a. Synonym: kif1-binding protein,kinesin family binding protein. Engineered: yes. Kinesin-like protein kif15. Chain: b. Synonym: kinesin-like protein 2,hklp2,kinesin-like protein 7, serologically defined breast cancer antigen ny-br-62. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: kifbp, kbp, kiaa1279, kif1bp. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: kif15, klp2, knsl7. Expression_system_taxid: 562

Authors:

J.Atherton,J.J.A.Hummel,N.Olieric,J.Locke,A.Pena,S.S.Rosenfeld, M.O.Steinmetz,C.C.Hoogenraad,C.A.Moores

Key ref:

J.Atherton et al. (2020). The mechanism of kinesin inhibition by kinesin-Bindin protein.. Elife, 9, . PubMed id: 33252036

Date:

08-Jul-20 Release date: 30-Dec-20

Protein chain

Q96EK5  (KBP_HUMAN) -  KIF-binding protein from Homo sapiens

Seq: 621 a.a.

Struc: 457 a.a.

Protein chain

Q9NS87  (KIF15_HUMAN) -  Kinesin-like protein KIF15 from Homo sapiens

Seq: 1388 a.a.

Struc: 315 a.a.*

* PDB and UniProt seqs differ at 6 residue positions (black crosses)