PDBsum entry 6ysh

Nuclear protein

PDB id: 6ysh

Contents

Protein chains

83 a.a.

Waters ×22

PDB id:

6ysh

Name:

Nuclear protein

Title:

Lamin a 1-70 coil1a dimer stabilized by c-terminal capping

Structure:

Prelamin-a/c,microtubule-associated protein rp/eb family member 1. Chain: a. Synonym: apc-binding protein eb1,end-binding protein 1,eb1. Engineered: yes. Prelamin-a/c,microtubule-associated protein rp/eb family member 1. Chain: b. Synonym: apc-binding protein eb1,end-binding protein 1,eb1.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: lmna, lmn1, mapre1. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562

Resolution:

2.83Å R-factor: 0.240 R-free: 0.281

Authors:

G.Stalmans,A.V.Lilina,S.V.Strelkov

Key ref:

G.Stalmans et al. (2020). Addressing the molecular mechanism of longitudinal la assembly using chimeric fusions.. Cells, 9, . PubMed id: 32645958

Date:

22-Apr-20 Release date: 02-Sep-20

Protein chains

P02545  (LMNA_HUMAN) -  Prelamin-A/C from Homo sapiens

Seq: 664 a.a.

Struc: 83 a.a.*

Protein chains

Q15691  (MARE1_HUMAN) -  Microtubule-associated protein RP/EB family member 1 from Homo sapiens

Seq: 268 a.a.

Struc: 83 a.a.*

* PDB and UniProt seqs differ at 76 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.?