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PDBsum entry 6yif

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protein ligands metals Protein-protein interface(s) links
Cell cycle PDB id
6yif

 

 

 

 

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Contents
Protein chains
130 a.a.
56 a.a.
37 a.a.
Ligands
ALA-ARG-TPO-LYS-
GLN
SO4 ×3
Metals
_ZN
Waters ×228
PDB id:
6yif
Name: Cell cycle
Title: Structure of chromosomal passenger complex (cpc) bound to phosphorylated histone 3 peptide at 1.8 a.
Structure: Baculoviral iap repeat-containing protein 5. Chain: a. Synonym: apoptosis inhibitor 4,apoptosis inhibitor survivin. Engineered: yes. Borealin. Chain: b. Synonym: cell division cycle-associated protein 8,dasra-b,hdasra-b, pluripotent embryonic stem cell-related gene 3 protein. Engineered: yes.
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: birc5, api4, iap4. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: codonplus (ril). Gene: cdca8, pescrg3. Expression_system_cell: bl21 codonplus (de3) ril.
Resolution:
1.81Å     R-factor:   0.183     R-free:   0.223
Authors: M.Serena,P.R.Elliott,F.A.Barr
Key ref: M.Serena et al. (2020). Molecular basis of mklp2-Dependent aurora b transport chromatin to the anaphase central spindle.. J cell biol, 219, . PubMed id: 32356865
Date:
01-Apr-20     Release date:   13-May-20    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
O15392  (BIRC5_HUMAN) -  Baculoviral IAP repeat-containing protein 5 from Homo sapiens
Seq:
Struc:
142 a.a.
130 a.a.
Protein chain
Pfam   ArchSchema ?
Q53HL2  (BOREA_HUMAN) -  Borealin from Homo sapiens
Seq:
Struc:
280 a.a.
56 a.a.
Protein chain
Pfam   ArchSchema ?
Q9NQS7  (INCE_HUMAN) -  Inner centromere protein from Homo sapiens
Seq:
Struc:
 
Seq:
Struc:
918 a.a.
37 a.a.
Key:    PfamA domain  Secondary structure

 

 

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