PDBsum entry 6y9d

Oxidoreductase

PDB id: 6y9d

Contents

Protein chains

(+ 6 more) 352 a.a.

Ligands

FES ×12

152 ×12

SCN ×12

EPE ×12

Metals

_FE ×12

Waters ×1002

PDB id:

6y9d

Name:

Oxidoreductase

Title:

Crystal structure of the quaternary ammonium rieske monooxygenase cnta in complex with substrate l-carnitine

Structure:

Carnitine monooxygenase oxygenase subunit. Chain: a, b, c, d, e, f, g, h, i, j, k, l. Synonym: carnitine monooxygenase alpha subunit. Engineered: yes

Source:

Acinetobacter baumannii. Organism_taxid: 470. Gene: anta_2, anta_1, anta_3, a7m79_02670, a7m90_13970, abuw_3074, b4r90_07590, b9x95_06095, bgc29_09330, c2u32_18540, c3415_14505, cbi29_00874, chq89_11265, cpi82_11190, csb70_0522, dli75_01970, dol94_04925, dva79_16365, e2533_13315, e2536_16135, e5294_15630, e5979_13670, ea685_07170, ea686_01565, ea706_03020, ea722_03860, ea746_003300, ewo92_12480, ewo96_16565, ewp49_15025, fd887_09300, fd913_14110, fju36_15000, fju42_16200, fju76_14830, fju79_08840,

Resolution:

1.97Å R-factor: 0.212 R-free: 0.247

Authors:

M.Quareshy,M.Shanmugam,T.D.Bugg,A.Cameron,Y.Chen

Key ref:

M.Quareshy et al. Structural basis of carnitine monooxygenase cnta subs specificity, Inhibition and inter-Subunit electron tr. J biol chem, . PubMed id: 33158989

Date:

06-Mar-20 Release date: 18-Nov-20

Protein chains

A0A059ZPP5  (A0A059ZPP5_ACIBA) -  Carnitine monooxygenase oxygenase subunit from Acinetobacter baumannii

Seq: 371 a.a.

Struc: 352 a.a.

Enzyme reactions

• Enzyme class: E.C.1.14.13.239 - carnitine monooxygenase.
• Reaction: (R)-carnitine + NADH + O2 + H⁺ = (3R)-3-hydroxy-4-oxobutanoate + trimethylamine + NAD⁺ + H2O

(R)-carnitine + NADH + O2 + H(+) = (3R)-3-hydroxy-4-oxobutanoate + trimethylamine + NAD(+) + H2O (Bound ligand (Het Group name = SCN) matches with 40.00% similarity)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site