PDBsum entry 6xtc

Hydrolase

PDB id: 6xtc

Contents

Protein chains

291 a.a.

Ligands

GOL ×2

SO4 ×35

Waters ×255

PDB id:

6xtc

Name:

Hydrolase

Title:

Crystal structure of haloalkane dehalogenase variant dhaa177 domain- swapped dimer type-3

Structure:

Haloalkane dehalogenase variant dhaa177 domain-swapped dimer type-3. Chain: a, b, c, d. Engineered: yes

Source:

Synthetic construct. Organism_taxid: 32630. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

2.54Å R-factor: 0.230 R-free: 0.289

Authors:

K.Markova,J.Damborsky,M.Marek

Key ref:

K.Markova et al. Structures of haloalkane dehalogenase variant dhaa115 dhaa177. To be published, .

Date:

16-Jan-20 Release date: 27-Jan-21

Protein chains

P0A3G2  (DHAA_RHORH) -  Haloalkane dehalogenase from Rhodococcus rhodochrous

Seq: 293 a.a.

Struc: 291 a.a.*

* PDB and UniProt seqs differ at 4 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.3.8.1.5 - haloalkane dehalogenase.
• Reaction: 1-haloalkane + H2O = a halide anion + a primary alcohol + H⁺

Molecule diagrams generated from .mol files obtained from the KEGG ftp site