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PDBsum entry 6th4
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protein ligands metals Protein-protein interface(s) links
Cell cycle PDB id
6th4

 

 

 

 

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Contents
Protein chains
428 a.a.
428 a.a.
128 a.a.
Ligands
SO4 ×7
GTP ×2
GDP ×2
N9B ×2
Metals
_MG ×2
Waters ×117
PDB id:
6th4
Name: Cell cycle
Title: Tubulin-inhibitor complex
Structure: Tubulin alpha chain. Chain: a, c. Tubulin beta chain. Chain: b, d. Stathmin-4. Chain: e. Synonym: stathmin-like protein b3,rb3. Engineered: yes. Mutation: yes
Source: Ovis aries. Sheep. Organism_taxid: 9940. Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: stmn4. Expressed in: escherichia coli. Expression_system_taxid: 562
Resolution:
2.12Å     R-factor:   0.194     R-free:   0.226
Authors: P.F.Varela,B.Gigant
Key ref: A.Stein et al. The b-Nor-Methylene colchicinoid pt-100 selectively i apoptosis in multidrug resistant cancer cells at low nanomolar concentration. To be published, .
Date:
18-Nov-19     Release date:   01-Dec-21    
PROCHECK
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 Headers
 References

Protein chains
No UniProt id for this chain
Struc: 428 a.a.
Protein chains
No UniProt id for this chain
Struc: 428 a.a.
Protein chain
Pfam   ArchSchema ?
P63043  (STMN4_RAT) -  Stathmin-4 from Rattus norvegicus
Seq:
Struc: 		189 a.a.
128 a.a.*
Key:    PfamA domain  Secondary structure
* PDB and UniProt seqs differ at 3 residue positions (black crosses)

 

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