PDBsum entry 6t1v

Transcription

PDB id: 6t1v

Contents

Protein chain

268 a.a.

Ligands

PRO-SER-LEU-LEU-LYS-LYS-LEU-LEU-LEU-ALA

EDK

Waters ×230

PDB id:

6t1v

Name:

Transcription

Title:

Structure of pparg h494y mutant in complex with gw1929

Structure:

Peroxisome proliferator-activated receptor gamma. Chain: a. Synonym: ppar-gamma,nuclear receptor subfamily 1 group c member 3. Engineered: yes. Mutation: yes. Peroxisome proliferator-activated receptor gamma coactivator 1-alpha. Chain: c. Synonym: ppargc-1-alpha,ligand effect modulator 6.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: pparg, nr1c3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606

Resolution:

2.21Å R-factor: 0.169 R-free: 0.196

Authors:

N.Rochel

Key ref:

N.Rochel Structure of a pparg mutant complex. To be published, .

Date:

06-Oct-19 Release date: 14-Apr-21

Protein chain

P37231  (PPARG_HUMAN) -  Peroxisome proliferator-activated receptor gamma from Homo sapiens

Seq: 505 a.a.

Struc: 268 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: E.C.?