PDBsum entry 6ouk

Lyase/lyase inhibitor

PDB id: 6ouk

Contents

Protein chain

257 a.a.

Ligands

N7J ×2

GOL ×2

Metals

_ZN

Waters ×248

PDB id:

6ouk

Name:

Lyase/lyase inhibitor

Title:

Carbonic anhydrase ii complexed with benzene sulfonamide mb10-580b

Structure:

Carbonic anhydrase 2. Chain: a. Synonym: carbonate dehydratase ii,carbonic anhydrasE C,cac,carbonic anhydrase ii,ca-ii. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

1.50Å R-factor: 0.169 R-free: 0.186

Authors:

A.Kota,R.Mckenna

Key ref:

A.Kota and r.mckenna Carbonic anhydrase ii complexed with benzene sulfonam mb10-580b. To be published, .

Date:

04-May-19 Release date: 06-May-20

Protein chain

P00918  (CAH2_HUMAN) -  Carbonic anhydrase 2 from Homo sapiens

Seq: 260 a.a.

Struc: 257 a.a.

Enzyme reactions

• Enzyme class: E.C.4.2.1.1 - carbonic anhydrase.
• Reaction: hydrogencarbonate + H⁺ = CO2 + H2O
• Cofactor: Zn(2+)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site