PDBsum entry 6nux

Immune system

PDB id: 6nux

Contents

Protein chains

270 a.a.

104 a.a.

Ligands

FOF

EDO ×3

Waters ×106

PDB id:

6nux

Name:

Immune system

Title:

Cd1a-lipid binary complex

Structure:

Cd1a protein. Chain: a. Engineered: yes. Beta-2-microglobulin. Chain: b. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: cd1a. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293s. Gene: b2m, cdabp0092, hdcma22p. Expression_system_cell_line: hek293s

Resolution:

2.20Å R-factor: 0.207 R-free: 0.248

Authors:

M.Wegrecki,J.Le Nours,J.Rossjohn

Key ref:

S.Nicolai et al. (2020). Human t cell response to cd1a and contact dermatitis allergens in botanical extracts and commercial skin c products.. Sci immunol, 5, . PubMed id: 31901073

Date:

03-Feb-19 Release date: 15-Jan-20

Protein chain

P06126  (CD1A_HUMAN) -  T-cell surface glycoprotein CD1a from Homo sapiens

Seq: 327 a.a.

Struc: 270 a.a.*

Protein chain

P61769  (B2MG_HUMAN) -  Beta-2-microglobulin from Homo sapiens

Seq: 119 a.a.

Struc: 104 a.a.

* PDB and UniProt seqs differ at 9 residue positions (black crosses)