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PDBsum entry 6n0r

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protein ligands Protein-protein interface(s) links
DNA binding protein, hydrolase PDB id
6n0r

 

 

 

 

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Contents
Protein chains
438 a.a.
Ligands
K8D ×2
EDO ×4
DMS
Waters ×730
PDB id:
6n0r
Name: DNA binding protein, hydrolase
Title: Crystal structure of tdp1 catalytic domain in complex with compound xz572
Structure: Tyrosyl-DNA phosphodiesterase 1. Chain: a, b. Synonym: tyr-DNA phosphodiesterase 1. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: tdp1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
1.54Å     R-factor:   0.170     R-free:   0.195
Authors: G.T.Lountos,X.Z.Zhao,E.Kiselev,J.E.Tropea,D.Needle,T.R.Burke Jr., Y.Pommier,D.S.Waugh
Key ref: G.T.Lountos et al. Crystal structure of tdp1 catalytic domain. To be published, .
Date:
07-Nov-18     Release date:   13-Nov-19    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q9NUW8  (TYDP1_HUMAN) -  Tyrosyl-DNA phosphodiesterase 1 from Homo sapiens
Seq:
Struc:
 
Seq:
Struc:
608 a.a.
438 a.a.
Key:    PfamA domain  Secondary structure

 Enzyme reactions 
   Enzyme class: E.C.3.1.4.-  - ?????
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

 

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