PDBsum entry 6md4

Transcription/transcription inhibitor

PDB id: 6md4

Contents

Protein chains

258 a.a.

Ligands

BRL

OLA

Waters ×224

PDB id:

6md4

Name:

Transcription/transcription inhibitor

Title:

Crystal structure of human ppargamma ligand binding domain in complex with rosiglitazone and oleic acid

Structure:

Peroxisome proliferator-activated receptor gamma. Chain: a, b. Synonym: ppar-gamma,nuclear receptor subfamily 1 group c member 3. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: pparg, nr1c3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

Resolution:

2.24Å R-factor: 0.242 R-free: 0.282

Authors:

J.Shang,D.J.Kojetin

Key ref:

j.shang and d.j.kojetin (2018). Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPAR gamma. Elife, 7, . PubMed id: 30575522

Date:

03-Sep-18 Release date: 09-Jan-19

Protein chains

P37231  (PPARG_HUMAN) -  Peroxisome proliferator-activated receptor gamma from Homo sapiens

Seq: 505 a.a.

Struc: 258 a.a.

Elife 7: (2018)

PubMed id: 30575522

Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPAR gamma.

j.shang, d.j.kojetin.

ABSTRACT

No abstract given.