PDBsum entry 6lzc

Hydrolase

PDB id: 6lzc

Contents

Protein chain

304 a.a.

Ligands

EYL

GOL ×3

Metals

_MG

_CO ×2

_NA

Waters ×183

PDB id:

6lzc

Name:

Hydrolase

Title:

Crystal structure of human methionine aminopeptidase (hsmetap1b) in complex with kv-p2-4h-05

Structure:

Methionine aminopeptidase 1. Chain: a. Synonym: metap 1,peptidase m 1. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: metap1, kiaa0094. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

1.35Å R-factor: 0.169 R-free: 0.197

Authors:

C.B.Sandeep,A.Addlagatta

Key ref:

C.B.Sandeep and a.addlagatta Crystal structure of human methionine aminopeptidase (hsmetap1b) in complex with an-P2-5h-06. To be published, . PubMed id: 34329997

Date:

18-Feb-20 Release date: 24-Feb-21

Protein chain

P53582  (MAP11_HUMAN) -  Methionine aminopeptidase 1 from Homo sapiens

Seq: 386 a.a.

Struc: 304 a.a.

Enzyme reactions

• Enzyme class: E.C.3.4.11.18 - methionyl aminopeptidase.
• Reaction: Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.
• Cofactor: Cobalt cation