PDBsum entry 6lvh

Hydrolase

PDB id: 6lvh

Contents

Protein chain

295 a.a.

Ligands

GOL ×3

Waters ×14

PDB id:

6lvh

Name:

Hydrolase

Title:

Crystal structure of methionine aminopeptidase from pyrococcus furiosus

Structure:

Methionine aminopeptidase. Chain: a. Synonym: metap,peptidase m. Engineered: yes. Mutation: yes

Source:

Pyrococcus furiosus (strain atcc 43587 / dsm 3638 / jcm 8422 / vc1). Organism_taxid: 186497. Strain: atcc 43587 / dsm 3638 / jcm 8422 / vc1. Gene: map, pf0541. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

3.20Å R-factor: 0.165 R-free: 0.214

Authors:

A.Addlagatta,C.B.Sandeep

Key ref:

A.Addlagatta and c.b.sandeep Crystal structure of methionine aminopeptidase from pyrococcus furiosus. To be published, .

Date:

03-Feb-20 Release date: 03-Feb-21

Protein chain

P56218  (MAP2_PYRFU) -  Methionine aminopeptidase from Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)

Seq: 295 a.a.

Struc: 295 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: E.C.3.4.11.18 - methionyl aminopeptidase.
• Reaction: Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.
• Cofactor: Cobalt cation