PDBsum entry 6in2

Transcription

PDB id: 6in2

Contents

Protein chain

124 a.a.

Ligands

ACT

O4B

Waters ×73

PDB id:

6in2

Name:

Transcription

Title:

Crystal structure of brd1 in complex with 18-crown-6

Structure:

Bromodomain-containing protein 1. Chain: a. Synonym: br140-like protein,bromodomain and phd finger-containing protein 2. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: brd1, brl, brpf2. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

1.75Å R-factor: 0.210 R-free: 0.248

Authors:

T.Yokoyama,Y.Kosaka,K.Matsumoto,R.Kitakami,Y.Nabeshima,M.Mizuguchi

Key ref:

T.Yokoyama et al. Crown ethers as transthyretin amyloidogenesis inhibit. To be published, .

Date:

24-Oct-18 Release date: 30-Oct-19

Protein chain

O95696  (BRD1_HUMAN) -  Bromodomain-containing protein 1 from Homo sapiens

Seq: 1058 a.a.

Struc: 124 a.a.*

* PDB and UniProt seqs differ at 8 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.?