PDBsum entry 6hj2

Nuclear protein

PDB id: 6hj2

Contents

Protein chain

274 a.a.

Ligands

P06

IPA

Waters ×78

PDB id:

6hj2

Name:

Nuclear protein

Title:

Crystal structure of hpxr in complex with dabrafenib

Structure:

Nuclear receptor subfamily 1 group i member 2. Chain: a. Synonym: orphan nuclear receptor par1,orphan nuclear receptor pxr, pregnane x receptor,steroid and xenobiotic receptor,sxr. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: nr1i2, pxr. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

Resolution:

2.28Å R-factor: 0.192 R-free: 0.232

Authors:

M.Granell,V.Delfosse,W.Bourguet

Key ref:

M.Granell et al. Crystal structure of hpxr in complex with dabrafenib. To be published, . PubMed id: 34958586

Date:

31-Aug-18 Release date: 25-Mar-20

Protein chain

O75469  (NR1I2_HUMAN) -  Nuclear receptor subfamily 1 group I member 2 from Homo sapiens

Seq: 434 a.a.

Struc: 274 a.a.

Enzyme reactions

• Enzyme class: E.C.?