PDBsum entry 6hg0

Hydrolase

PDB id: 6hg0

Contents

Protein chain

388 a.a.

Ligands

NAG-NAG-BMA-MAN-MAN-MAN-MAN-MAN-MAN-MAN

NAG-NAG ×2

GOL ×4

PO4

SIA ×2

Metals

__K

_CA ×2

Waters ×729

PDB id:

6hg0

Name:

Hydrolase

Title:

Influenza a virus n9 neuraminidase complex with nana (tern/australia).

Structure:

Neuraminidase. Chain: a. Ec: 3.2.1.18

Source:

Influenza a virus (strain a/tern/australia/g70c/1975 h11n9). Organism_taxid: 384509

Resolution:

1.30Å R-factor: 0.093 R-free: 0.120

Authors:

M.T.Salinger,J.R.Hobbs,J.W.Murray,W.G.Laver,P.Kuhn,E.F.Garman

Key ref:

M.T.Salinger et al. High resolution structures of viral neuraminidase wit bound in the active site. (In preparation). To be published, .

Date:

22-Aug-18 Release date: 29-Aug-18

Protein chain

P03472  (NRAM_I75A5) -  Neuraminidase from Influenza A virus (strain A/Tern/Australia/G70C/1975 H11N9)

Seq: 470 a.a.

Struc: 388 a.a.

Enzyme reactions

• Enzyme class: E.C.3.2.1.18 - exo-alpha-sialidase.
• Reaction: Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)-glycosidic linkages of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.