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PDBsum entry 6hex
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protein ligands links
Transferase PDB id
6hex

 

 

 

 

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Contents
Protein chain
268 a.a.
Ligands
G02
Waters ×311
PDB id:
6hex
Name: Transferase
Title: Crystal structure of ephrin a2 (epha2) receptor protein kinase with the nvp-bhg712 derivative atmm006
Structure: Ephrin type-a receptor 2. Chain: a. Engineered: yes
Source: Homo sapiens. Organism_taxid: 9606. Gene: epha2, eck. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108
Resolution:
1.41Å     R-factor:   0.160     R-free:   0.179
Authors: D.Kudlinzki,A.Troester,K.Witt,V.L.Linhard,S.L.Gande,K.Saxena, H.Schwalbe
Key ref: A.Troester et al. Effects of nvp-Bhg712 chemical modifications on epha2 binding and affinity. To be published, .
Date:
20-Aug-18     Release date:   28-Aug-19    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P29317  (EPHA2_HUMAN) -  Ephrin type-A receptor 2 from Homo sapiens
Seq:
Struc: 		 
Seq:
Struc: 		976 a.a.
268 a.a.
Key:    PfamA domain  Secondary structure

 Enzyme reactions 
   Enzyme class: E.C.2.7.10.1  - receptor protein-tyrosine kinase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H+
L-tyrosyl-[protein]
 + ATP
 = O-phospho-L-tyrosyl-[protein]
 + ADP
 + H(+)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 

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