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PDBsum entry 6edf
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PDB id:
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Transferase
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Title:
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Fragment of a tyrosine-protein kinase
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Structure:
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Fyn. Chain: a. Synonym: tyrosine-protein kinase fyn. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Resolution:
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1.40Å
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R-factor:
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0.145
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R-free:
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0.172
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Authors:
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W.Tempel,H.Huang,I.Sochirca,K.Liu,C.Bountra,C.H.Arrowsmith, A.M.Edwards,S.S.Sidhu,J.Min,Structural Genomics Consortium (Sgc)
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Key ref:
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W.Tempel
et al.
Fragment of a tyrosine-Protein kinase.
To be published,
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Date:
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09-Aug-18
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Release date:
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29-Aug-18
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PROCHECK
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Headers
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References
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P06241
(FYN_HUMAN) -
Tyrosine-protein kinase Fyn from Homo sapiens
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Seq:
Struc:
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537 a.a.
77 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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*
PDB and UniProt seqs differ
at 21 residue positions (black
crosses)
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Enzyme class:
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E.C.2.7.10.2
- non-specific protein-tyrosine kinase.
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Reaction:
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L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H+
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L-tyrosyl-[protein]
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+
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ATP
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=
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O-phospho-L-tyrosyl-[protein]
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+
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ADP
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+
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H(+)
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
