PDBsum entry 6d0c

Transcription

PDB id: 6d0c

Contents

Protein chains

109 a.a.

110 a.a.

Waters ×128

PDB id:

6d0c

Name:

Transcription

Title:

Crystal structure of hif2a-b :Arnt-b Complex

Structure:

Endothelial pas domain-containing protein 1. Chain: a. Fragment: residues 239-350. Synonym: epas-1,basic-helix-loop-helix-pas protein mop2,class e basic helix-loop-helix protein 73,bhlhe73,hif-1-alpha-like factor,hlf, hypoxia-inducible factor 2-alpha,hif2-alpha,member of pas protein 2, pas domain-containing protein 2. Engineered: yes. Mutation: yes.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: epas1, bhlhe73, hif2a, mop2, pasd2. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: arnt, bhlhe2. Expression_system_taxid: 562

Resolution:

1.50Å R-factor: 0.208 R-free: 0.240

Authors:

X.Du

Key ref:

X.Du Crystal structure of pt1940 bound to hif2a-B:Arnt-B Complex. To be published, .

Date:

10-Apr-18 Release date: 31-Oct-18

Protein chain

Q99814  (EPAS1_HUMAN) -  Endothelial PAS domain-containing protein 1 from Homo sapiens

Seq: 870 a.a.

Struc: 109 a.a.*

Protein chain

P27540  (ARNT_HUMAN) -  Aryl hydrocarbon receptor nuclear translocator from Homo sapiens

Seq: 789 a.a.

Struc: 110 a.a.*

* PDB and UniProt seqs differ at 5 residue positions (black crosses)