PDBsum entry 6bs7

Ligase

PDB id

6bs7

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Contents

			Protein chain

					390 a.a.

			Waters ×129

PDB id:

6bs7

Links

Name:

Ligase

Title:

Crystal structure of adenylosuccinate synthetase from legionella pneumophila philadelphia 1

Structure:

Adenylosuccinate synthetase. Chain: a. Synonym: adss,imp--aspartate ligase. Engineered: yes

Source:

Legionella pneumophila. Organism_taxid: 446. Atcc: 33152. Gene: pura. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768.

Resolution:

1.95Å

R-factor:

0.189

R-free:

0.232

Authors:

Seattle Structural Genomics Center For Infectious Disease (Ssgcid)

Key ref:

J.Abendroth et al. Crystal structure of adenylosuccinate synthetase from legionella pneumophila. To be published, .

Date:

01-Dec-17

Release date:

17-Jan-18

PROCHECK

	Headers

	References

Protein chain

Q8RNM2 (PURA_LEGPN) - Adenylosuccinate synthetase from Legionella pneumophila

Seq: Struc:					431 a.a. 390 a.a.

Key:

PfamA domain

Secondary structure



		Enzyme reactions

Enzyme class:

E.C.6.3.4.4 - adenylosuccinate synthase.

[IntEnz] [ExPASy] [KEGG] [BRENDA]

Pathway:

AMP and GMP Biosynthesis

Reaction:

IMP + L-aspartate + GTP = N₆-(1,2-dicarboxyethyl)-AMP + GDP + phosphate + 2 H⁺

IMP	+	L-aspartate	+	GTP	=	N(6)-(1,2-dicarboxyethyl)-AMP	+	GDP	+	phosphate	+	2 × H(+)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site