PDBsum entry 6bpf

Hydrolase/hydrolase inhibitor

PDB id: 6bpf

Contents

Protein chain

265 a.a.

Ligands

NXL

Waters ×295

PDB id:

6bpf

Name:

Hydrolase/hydrolase inhibitor

Title:

Ctx-m-151 class a extended-spectrum beta-lactamase crystal structure in complex with avibactam at 1.32 angstrom resolution

Structure:

Beta-lactamase. Chain: a. Engineered: yes

Source:

Salmonella enterica. Organism_taxid: 28901. Gene: blactx-m151. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

Resolution:

1.32Å R-factor: 0.189 R-free: 0.213

Authors:

P.Power,B.Ghiglione,M.M.Rodriguez,G.Gutkind,Y.Ishii,R.A.Bonomo, S.Klinke

Key ref:

P.Power et al. Ctx-M-151 class a extended-Spectrum beta-Lactamase cr structure in complex with avibactam at 1.32 angstrom resolution.. To be published, . PubMed id: 33431411

Date:

23-Nov-17 Release date: 28-Nov-18

Protein chain

A0A077KT80  (A0A077KT80_SALER) -  Beta-lactamase from Salmonella enterica

Seq: 304 a.a.

Struc: 265 a.a.

Enzyme reactions

• Enzyme class: E.C.3.5.2.6 - beta-lactamase.
• Pathway: Penicillin Biosynthesis and Metabolism
• Reaction: a beta-lactam + H2O = a substituted beta-amino acid
• Cofactor: Zn(2+)