PDBsum entry 6bmc

Transferase

PDB id: 6bmc

Contents

Protein chains

380 a.a.

Ligands

PEP ×2

Metals

_CO ×2

_CL

Waters ×13

PDB id:

6bmc

Name:

Transferase

Title:

The structure of a dimeric type ii dah7ps associated with pyocyanin biosynthesis in pseudomonas aeruginosa

Structure:

Phospho-2-dehydro-3-deoxyheptonate aldolase. Chain: a, b. Synonym: 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase. Engineered: yes

Source:

Pseudomonas aeruginosa. Organism_taxid: 287. Gene: phzc, aroh_3, aoy09_05716, caz10_37830, paerug_e15_london_28_01_14_08300. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.

Resolution:

2.70Å R-factor: 0.250 R-free: 0.290

Authors:

O.W.Sterritt,G.B.Jameson,E.J.Parker

Key ref:

O.W.Sterritt et al. The short-Form type ii dah7ps frompseudomonas aerugin associated with phenazine biosynthesis, Suggests reclassification of type ii enzymes.. Biosci rep, . PubMed id: 30242059

Date:

14-Nov-17 Release date: 03-Oct-18

Protein chains

G3XCJ9  (G3XCJ9_PSEAI) -  Phospho-2-dehydro-3-deoxyheptonate aldolase from Pseudomonas aeruginosa

Seq: 405 a.a.

Struc: 380 a.a.

Enzyme reactions

• Enzyme class: E.C.2.5.1.54 - 3-deoxy-7-phosphoheptulonate synthase.
• Pathway: Shikimate and Chorismate Biosynthesis
• Reaction: D-erythrose 4-phosphate + phosphoenolpyruvate + H2O = 7-phospho-2- dehydro-3-deoxy-D-arabino-heptonate + phosphate

D-erythrose 4-phosphate + phosphoenolpyruvate + H2O (Bound ligand (Het Group name = PEP) corresponds exactly) = 7-phospho-2- dehydro-3-deoxy-D-arabino-heptonate + phosphate

Molecule diagrams generated from .mol files obtained from the KEGG ftp site