PDBsum entry 6a1c

Transferase

PDB id: 6a1c

Contents

Protein chain

334 a.a.

Ligands

9NX

EDO ×24

EDO-EDO

Metals

_NA

Waters ×186

PDB id:

6a1c

Name:

Transferase

Title:

Crystal structure of the ck2a1-go289 complex

Structure:

Casein kinase ii subunit alpha. Chain: a. Synonym: ck ii alpha. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: csnk2a1, ck2a1. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

1.68Å R-factor: 0.140 R-free: 0.196

Authors:

T.Kinoshita,M.Tsuyuguchi

Date:

07-Jun-18 Release date: 06-Mar-19

Protein chain

P68400  (CSK21_HUMAN) -  Casein kinase II subunit alpha from Homo sapiens

Seq: 391 a.a.

Struc: 334 a.a.

Enzyme reactions

• Enzyme class: E.C.2.7.11.1 - non-specific serine/threonine protein kinase.
• Reaction:
  1. L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H⁺
  2. L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H⁺

Molecule diagrams generated from .mol files obtained from the KEGG ftp site