PDBsum entry 6dfs

Immune system

PDB id: 6dfs

Contents

Protein chains

207 a.a.

241 a.a.

181 a.a.

150 a.a.

Ligands

NAG

Waters ×19

PDB id:

6dfs

Name:

Immune system

Title:

Mouse tcr i.29 in complex with iag7-p8e9e6ss

Structure:

Mouse tcr alpha chain. Chain: a. Engineered: yes. Mouse tcr beta chain. Chain: b. Engineered: yes. H-2 class ii histocompatibility antigen, a-d alpha chain. Chain: c. Engineered: yes.

Source:

Mus musculus. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 866768. Mouse. Gene: h2-aa. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: h2-ab1.

Resolution:

3.10Å R-factor: 0.242 R-free: 0.285

Authors:

Y.Wang,S.Dai

Key ref:

Y.Wang et al. (2019). How c-Terminal additions to insulin b-Chain fragments superagonists for t cells in mouse and human type 1 diabetes.. Sci immunol, 4, . PubMed id: 30952805

Date:

15-May-18 Release date: 17-Apr-19

Protein chain

No UniProt id for this chain

Struc: 207 a.a.

Protein chain

No UniProt id for this chain

Struc: 241 a.a.

Protein chain

P04228  (HA2D_MOUSE) -  H-2 class II histocompatibility antigen, A-D alpha chain from Mus musculus

Seq: 256 a.a.

Struc: 181 a.a.*

Protein chain

Q31135  (Q31135_MOUSE) -  H2-Ab1 protein from Mus musculus

Seq: 263 a.a.

Struc: 150 a.a.*

* PDB and UniProt seqs differ at 13 residue positions (black crosses)