PDBsum entry 6baa

Metal transport

PDB id: 6baa

Contents

Protein chains

321 a.a.

1317 a.a.

Ligands

ATP ×4

GBM ×4

PDB id:

6baa

Name:

Metal transport

Title:

Cryo-em structure of the pancreatic beta-cell katp channel bound to atp and glibenclamide

Structure:

Atp-sensitive inward rectifier potassium channel 11. Chain: a, b, c, d. Synonym: bir,inward rectifier k(+) channel kir6.2,potassium channel, inwardly rectifying subfamily j member 11. Engineered: yes. Atp-binding cassette sub-family c member 8. Chain: e, f, g, h. Synonym: sulfonylurea receptor 1. Engineered: yes

Source:

Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: kcnj11. Expressed in: rattus norvegicus. Expression_system_taxid: 10116. Expression_system_cell_line: ins-1. Cricetus cricetus. Black-bellied hamster.

Authors:

G.M.Martin,C.Yoshioka,S.L.Shyng

Key ref:

G.M.Martin et al. (2017). Anti-Diabetic drug binding site in a mammalian katp c revealed by cryo-Em.. Elife, 6, . PubMed id: 29035201

Date:

12-Oct-17 Release date: 01-Nov-17

Protein chains

P70673  (KCJ11_RAT) -  ATP-sensitive inward rectifier potassium channel 11 from Rattus norvegicus

Seq: 390 a.a.

Struc: 321 a.a.*

Protein chains

Q09427  (ABCC8_CRICR) -  ATP-binding cassette sub-family C member 8 from Cricetus cricetus

Seq: 1582 a.a.

Struc: 1317 a.a.

* PDB and UniProt seqs differ at 1 residue position (black cross)