PDBsum entry 6b8s

Oxidoreductase

PDB id: 6b8s

Contents

Protein chains

335 a.a.

Ligands

FMN ×2

PGE ×2

Waters ×118

PDB id:

6b8s

Name:

Oxidoreductase

Title:

Crystal structure of dihydroorotate dehydrogenase from helicobacter pylori with bound fmn

Structure:

Dihydroorotate dehydrogenase (quinone). Chain: a, b. Fragment: hepyc.00487.A.B1. Synonym: dhodehase,dhodase,dihydroorotate oxidase. Engineered: yes

Source:

Helicobacter pylori (strain g27). Organism_taxid: 563041. Strain: g27. Gene: pyrd, hpg27_417. Expressed in: escherichia coli. Expression_system_taxid: 469008.

Resolution:

2.25Å R-factor: 0.185 R-free: 0.239

Authors:

Seattle Structural Genomics Center For Infectious Disease (Ssgcid)

Key ref:

D.M.Dranow et al. Crystal structure of dihydroorotate dehydrogenase fro helicobacter pylori with bound fmn. To be published, . PubMed id: 39960828

Date:

09-Oct-17 Release date: 22-Nov-17

Protein chains

B5Z6I2  (PYRD_HELPG) -  Dihydroorotate dehydrogenase (quinone) from Helicobacter pylori (strain G27)

Seq: 351 a.a.

Struc: 335 a.a.

Enzyme reactions

• Enzyme class: E.C.1.3.5.2 - dihydroorotate dehydrogenase (quinone).
• Reaction: (S)-dihydroorotate + a quinone = orotate + a quinol
• Cofactor: FMN

FMN (Bound ligand (Het Group name = FMN) corresponds exactly)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site