PDBsum entry 5y1h

Hydrolase

PDB id: 5y1h

Contents

Protein chain

890 a.a.

Ligands

GOL ×3

E8C

Metals

_MG ×3

_ZN

Waters ×561

PDB id:

5y1h

Name:

Hydrolase

Title:

Crystal structure of plasmodium falciparum aminopeptidase n in complex with (s)-2-(3-(2,4-difluorobenzyl)ureido)-n-hydroxy-4- methylpentanamide

Structure:

M1 family aminopeptidase. Chain: a. Fragment: unp residues 195-1085. Synonym: pfa-m1. Engineered: yes

Source:

Plasmodium falciparum. Organism_taxid: 186763. Strain: isolate fcb1 / columbia. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

1.73Å R-factor: 0.163 R-free: 0.201

Authors:

A.K.Marapaka,Y.Zhang,A.Addlagatta

Key ref:

A.K.Marapaka and a.addlagatta Crystal structure of plasmodium falciparum aminopepti in complex with (s)-2-(3-(2,4-Difluorobenzyl)ureido) -N-Hydroxy-4-Methylpentanamide. To be published, .

Date:

20-Jul-17 Release date: 01-Aug-18

Protein chain

O96935  (AMP1_PLAFQ) -  Aminopeptidase N from Plasmodium falciparum (isolate 3D7)

Seq: 1085 a.a.

Struc: 890 a.a.

Enzyme reactions

• Enzyme class: E.C.3.4.11.- - ?????