PDBsum entry 5ugm

Transcription

PDB id: 5ugm

Contents

Protein chains

271 a.a.

Ligands

8A7 ×4

KNA ×2

Waters ×473

PDB id:

5ugm

Name:

Transcription

Title:

Crystal structure of human ppargamma ligand binding domain in complex with edaglitazone

Structure:

Peroxisome proliferator-activated receptor gamma. Chain: a, b. Fragment: unp residues 235-505. Synonym: ppar-gamma,nuclear receptor subfamily 1 group c member 3. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: pparg, nr1c3. Expressed in: escherichia coli. Expression_system_taxid: 469008.

Resolution:

2.10Å R-factor: 0.182 R-free: 0.216

Authors:

J.Shang,D.J.Kojetin

Key ref:

j.shang and d.j.kojetin (2018). Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPAR gamma. Elife, 7, . PubMed id: 30575522

Date:

09-Jan-17 Release date: 17-Jan-18

Protein chains

P37231  (PPARG_HUMAN) -  Peroxisome proliferator-activated receptor gamma from Homo sapiens

Seq: 505 a.a.

Struc: 271 a.a.

Enzyme reactions

• Enzyme class: E.C.?

Elife 7: (2018)

PubMed id: 30575522

Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPAR gamma.

j.shang, d.j.kojetin.

ABSTRACT

No abstract given.