PDBsum entry 5u3l

Immune system/viral protein

PDB id: 5u3l

Contents

Protein chains

223 a.a.

214 a.a.

19 a.a.

Waters ×213

PDB id:

5u3l

Name:

Immune system/viral protein

Title:

Crystal structure of dh511.2 fab in complex with HIV-1 gp41 mper 670- 683 peptide

Structure:

Dh511.2 fab heavy chain. Chain: h, a. Engineered: yes. Dh511.2 fab light chain. Chain: l, b. Engineered: yes. Gp41 mper peptide. Chain: p, c. Fragment: gp41 656-683.

Source:

Homo sapiens. Organism_taxid: 9606. Gene: igg heavy chain. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek 293. Gene: igg light chain. Synthetic: yes. Human immunodeficiency virus 1.

Resolution:

2.17Å R-factor: 0.206 R-free: 0.231

Authors:

G.Ofek,L.Wu,C.S.Lougheed,L.D.Williams,N.I.Nicely,B.F.Haynes

Key ref:

L.D.Williams et al. Potent and broad HIV neutralizing antibodies in memor cells and plasma. Sci immunol, . PubMed id: 28783671

Date:

02-Dec-16 Release date: 15-Feb-17

Protein chains

No UniProt id for this chain

Struc: 223 a.a.

Protein chains

No UniProt id for this chain

Struc: 214 a.a.

Protein chains

Q73372  (ENV_HV1B9) -  Envelope glycoprotein gp160 from Human immunodeficiency virus type 1 group M subtype B (strain 89.6)

Seq: 853 a.a.

Struc: 19 a.a.*

* PDB and UniProt seqs differ at 5 residue positions (black crosses)