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PDBsum entry 5svk
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Membrane protein
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PDB id
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5svk
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PDB id:
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| Name: |
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Membrane protein
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Title:
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Crystal structure of the atp-gated human p2x3 ion channel in the atp- bound, open state
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Structure:
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P2x purinoceptor 3. Chain: a, b. Synonym: p2x3,atp receptor,purinergic receptor. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: p2rx3. Expressed in: homo sapiens. Expression_system_taxid: 9606
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Resolution:
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2.77Å
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R-factor:
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0.202
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R-free:
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0.228
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Authors:
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S.E.Mansoor,W.Lu,W.Oosterheert,M.Shekhar,E.Tajkhorshid,E.Gouaux
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Key ref:
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S.E.Mansoor
et al.
(2016).
X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature,
538,
66-71.
PubMed id:
DOI:
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Date:
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06-Aug-16
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Release date:
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28-Sep-16
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PROCHECK
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Headers
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References
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P56373
(P2RX3_HUMAN) -
P2X purinoceptor 3 from Homo sapiens
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Seq:
Struc:
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397 a.a.
357 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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*
PDB and UniProt seqs differ
at 3 residue positions (black
crosses)
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DOI no:
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Nature
538:66-71
(2016)
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PubMed id:
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X-ray structures define human P2X3 receptor gating cycle and antagonist action.
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S.E.Mansoor,
W.Lü,
W.Oosterheert,
M.Shekhar,
E.Tajkhorshid,
E.Gouaux.
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ABSTRACT
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Links
