PDBsum entry 5sql

Viral protein

PDB id: 5sql

Contents

Protein chains

167 a.a.

Ligands

QSL ×2

Waters ×548

PDB id:

5sql

Name:

Viral protein

Title:

Pandda analysis group deposition -- crystal structure of sars-cov-2 nsp3 macrodomain in complex with z2689779890

Structure:

Non-structural protein 3. Chain: a, b. Synonym: nsp3, pl2-pro, papain-like protease, papain-like proteinase, pl-pro. Engineered: yes. Other_details: his6 purification tag and linker (mhhhhhhssgvdlgtenlyfq) cleaved with tev protease

Source:

Severe acute respiratory syndrome coronavirus 2. Organism_taxid: 2697049. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

Resolution:

1.05Å R-factor: 0.134 R-free: 0.150

Authors:

G.J.Correy,J.S.Fraser

Key ref:

S.Gahbauer et al. Structure-Based inhibitor optimization for the nsp3 macrodomain of sars-Cov-2. Biorxiv, . PubMed id: 35794891

Date:

09-Jun-22 Release date: 06-Jul-22

Protein chains

P0DTD1  (R1AB_SARS2) -