PDBsum entry 5s8h

Signaling protein

PDB id: 5s8h

Contents

Protein chain

119 a.a.

Ligands

D4V

Waters ×186

PDB id:

5s8h

Name:

Signaling protein

Title:

Xchem group deposition -- crystal structure of the second bromodomain of pleckstrin homology domain interacting protein (phip) in complex with n00964e (space group c2)

Structure:

Ph-interacting protein. Chain: a. Synonym: phip,ddb1- and cul4-associated factor 14,irs-1 ph domain- binding protein,wd repeat-containing protein 11. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: phip, dcaf14, wdr11. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

1.29Å R-factor: 0.166 R-free: 0.200

Authors:

T.Krojer,R.Talon,M.Fairhead,A.Szykowska,N.A.Burgess-Brown, P.E.Brennan,C.H.Arrowsmith,A.M.Edwards,C.Bountra,F.Von Delft

Key ref:

T.Krojer et al. Xchem group deposition. To be published, .

Date:

17-Dec-20 Release date: 13-Jan-21

Protein chain

Q8WWQ0  (PHIP_HUMAN) -  PH-interacting protein from Homo sapiens

Seq: 1821 a.a.

Struc: 119 a.a.