PDBsum entry 5r4c

Hydrolase

PDB id: 5r4c

Contents

Protein chains

131 a.a.

95 a.a.

Ligands

CYS-GLY-VAL-PRO-ALA-ILE-GLN-PRO-VAL-LEU

SER-TRP-PRO-TRP

THR-PRO-GLY-VAL-TYR

SO4

Metals

IOD

Waters ×163

PDB id:

5r4c

Name:

Hydrolase

Title:

Crystal structure of gamma-chymotrypsin at ph 9, room temperature

Structure:

Gamma-chymotrypsin. Chain: a. Gamma-chymotrypsin. Chain: b. Gamma-chymotrypsin. Chain: c. Peptide swpw. Chain: d. Peptide tpgvy.

Source:

Bos taurus. Bovine. Organism_taxid: 9913. Organism_taxid: 9913

Resolution:

1.15Å R-factor: 0.113 R-free: 0.124

Authors:

C.A.Kreinbring,M.A.Wilson,A.Y.Kovalevsky,M.P.Blakeley,S.Z.Fisher, L.M.Lazar,A.G.Moulin,W.R.Novak,G.A.Petsko,D.Ringe

Key ref:

C.A.Kreinbring et al. Effect of temperature and ph on ionizable residues in gamma-Chymotrypsin: a X-Ray and neutron crystallograp study. To be published, .

Date:

18-Feb-20 Release date: 01-Sep-21

Protein chain

P00766  (CTRA_BOVIN) -  Chymotrypsinogen A from Bos taurus

Seq: 245 a.a.

Struc: 131 a.a.

Protein chain

P00766  (CTRA_BOVIN) -  Chymotrypsinogen A from Bos taurus

Seq: 245 a.a.

Struc: 95 a.a.

Enzyme reactions

• Enzyme class: Chains B, C: E.C.3.4.21.1 - chymotrypsin.
• Reaction: Preferential cleavage: Tyr-|-Xaa, Trp-|-Xaa, Phe-|-Xaa, Leu-|-Xaa.