PDBsum entry 5q4z

Hydrolase

PDB id: 5q4z

Contents

Protein chain

341 a.a.

Ligands

MLI

Metals

_NI

Waters ×310

PDB id:

5q4z

Name:

Hydrolase

Title:

Pandda analysis group deposition -- crystal structure of dclre1a after initial refinement with no ligand modelled (structure 100)

Structure:

Dclre1a. Chain: a. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: dclre1a, kiaa0086, snm1, snm1a. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108

Resolution:

1.60Å R-factor: 0.189 R-free: 0.221

Authors:

J.A.Newman,H.Aitkenhead,S.Y.Lee,K.Kupinska,N.Burgess-Brown,R.Tallon, T.Krojer,F.Von Delft,C.H.Arrowsmith,A.Edwards,C.Bountra,O.Gileadi

Key ref:

J.A.Newman et al. Pandda analysis group deposition. To be published, .

Date:

25-May-17 Release date: 08-Aug-18

Protein chain

Q6PJP8  (DCR1A_HUMAN) -  DNA cross-link repair 1A protein from Homo sapiens

Seq: 1040 a.a.

Struc: 341 a.a.

Enzyme reactions

• Enzyme class: E.C.3.5.2.6 - beta-lactamase.
• Pathway: Penicillin Biosynthesis and Metabolism
• Reaction: a beta-lactam + H2O = a substituted beta-amino acid
• Cofactor: Zn(2+)