PDBsum entry 5lpy

Transferase

PDB id

5lpy

Loading ...

Contents

			Protein chain

					286 a.a.

			Ligands

					ATP

			Waters ×10

PDB id:

5lpy

Links

Name:

Transferase

Title:

Crystal structure of the bri1 kinase domain (865-1160) in complex with atp from arabidopsis thaliana

Structure:

Protein brassinosteroid insensitive 1. Chain: a. Synonym: atbri1,brassinosteroid lrr receptor kinase. Engineered: yes. Mutation: yes

Source:

Arabidopsis thaliana. Mouse-ear cress. Organism_taxid: 3702. Gene: bri1, at4g39400, f23k16.30. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: ril.

Resolution:

2.30Å

R-factor:

0.203

R-free:

0.248

Authors:

D.Bojar,J.Martinez,M.Hothorn

Key ref:

D.Bojar et al. Crystal structure of the bri1 kinase domain (865-1160 complex with ATP from arabidopsis thaliana. To be published, .

Date:

15-Aug-16

Release date:

24-Aug-16

Supersedes:

4oab

PROCHECK

	Headers

	References

Protein chain

O22476 (BRI1_ARATH) - Protein BRASSINOSTEROID INSENSITIVE 1 from Arabidopsis thaliana

Seq: Struc:

Seq: Struc:

Seq: Struc:					1196 a.a. 286 a.a.*

Key:

PfamA domain

Secondary structure

* PDB and UniProt seqs differ at 2 residue positions (black crosses)



		Enzyme reactions

Enzyme class 2:

E.C.2.7.10.1 - receptor protein-tyrosine kinase.

[IntEnz] [ExPASy] [KEGG] [BRENDA]

Reaction:

L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H⁺

L-tyrosyl-[protein] Bound ligand (Het Group name = ATP) corresponds exactly	+	ATP	=	O-phospho-L-tyrosyl-[protein]	+	ADP	+	H(+)

Enzyme class 3:

E.C.2.7.11.1 - non-specific serine/threonine protein kinase.

[IntEnz] [ExPASy] [KEGG] [BRENDA]

Reaction:

1.	L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H⁺
2.	L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H⁺

L-seryl-[protein] Bound ligand (Het Group name = ATP) corresponds exactly	+	ATP	=	O-phospho-L-seryl-[protein]	+	ADP	+	H(+)

L-threonyl-[protein] Bound ligand (Het Group name = ATP) corresponds exactly	+	ATP	=	O-phospho-L-threonyl-[protein]	+	ADP	+	H(+)

Note, where more than one E.C. class is given (as above), each may correspond to a different protein domain or, in the case of polyprotein precursors, to a different mature protein.

Molecule diagrams generated from .mol files obtained from the KEGG ftp site