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PDBsum entry 5kmh

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protein ligands metals Protein-protein interface(s) links
Transport protein PDB id
5kmh

 

 

 

 

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Contents
Protein chains
219 a.a.
Ligands
MC3 ×6
PX6 ×4
6U8
Metals
_CA ×3
PDB id:
5kmh
Name: Transport protein
Title: Structure of cavab in complex with br-verapamil
Structure: Ion transport protein. Chain: a, b, c, d. Engineered: yes
Source: Arcobacter butzleri (strain rm4018). Organism_taxid: 367737. Strain: rm4018. Gene: abu_1752. Expressed in: trichoplusia ni. Expression_system_taxid: 7111.
Resolution:
3.20Å     R-factor:   0.253     R-free:   0.294
Authors: L.Tang,T.M.Gamal El-Din,T.M.Swanson,D.C.Pryde,T.Scheuer,N.Zheng, W.A.Catterall
Key ref: L.Tang et al. (2016). Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs. Nature, 537, 117-121. PubMed id: 27556947 DOI: 10.1038/nature19102
Date:
27-Jun-16     Release date:   31-Aug-16    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
A8EVM5  (A8EVM5_ARCB4) -  Ion transport protein from Aliarcobacter butzleri (strain RM4018)
Seq:
Struc:
267 a.a.
219 a.a.*
Key:    PfamA domain  Secondary structure
* PDB and UniProt seqs differ at 3 residue positions (black crosses)

 

 
DOI no: 10.1038/nature19102 Nature 537:117-121 (2016)
PubMed id: 27556947  
 
 
Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs.
L.Tang, T.M.Gamal El-Din, T.M.Swanson, D.C.Pryde, T.Scheuer, N.Zheng, W.A.Catterall.
 
  ABSTRACT  
 
No abstract given.

 

 

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