PDBsum entry 5k5f

DNA binding protein

PDB id: 5k5f

Contents

Protein chain

122 a.a.

PDB id:

5k5f

Name:

DNA binding protein

Title:

Nmr structure of the hltf hiran domain

Structure:

Helicase-like transcription factor. Chain: a. Fragment: residues 51-171. Synonym: DNA-binding protein/plasminogen activator inhibitor 1 regulator,hip116,ring finger protein 80,swi/snf-related matrix- associated actin-dependent regulator of chromatin subfamily a member 3,sucrose nonfermenting protein 2-like 3. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: hltf, hip116a, rnf80, smarca3, snf2l3, zbu1. Expressed in: escherichia coli. Expression_system_taxid: 562

NMR struc:

20 models

Authors:

I.Bezsonova,D.Neculai,D.Korzhnev,J.Weigelt,C.Bountra,A.Edwards, C.Arrowsmith,S.Dhe-Paganon,Structural Genomics Consortium (Sgc)

Key ref:

I.Bezsonova et al. Nmr structure of the hltf hiran domain. To be published, .

Date:

23-May-16 Release date: 08-Jun-16

Supersedes:

2l1i

Protein chain

Q14527  (HLTF_HUMAN) -  Helicase-like transcription factor from Homo sapiens

Seq: 1009 a.a.

Struc: 122 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class 1: E.C.2.3.2.27 - RING-type E3 ubiquitin transferase.
• Reaction: S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N₆- ubiquitinyl-[acceptor protein]-L-lysine
• Enzyme class 2: E.C.3.6.4.- - ?????

Note, where more than one E.C. class is given (as above), each may correspond to a different protein domain or, in the case of polyprotein precursors, to a different mature protein.