PDBsum entry 5jpw

Motor protein

PDB id: 5jpw

Contents

Protein chains

143 a.a.

PDB id:

5jpw

Name:

Motor protein

Title:

Molecular basis for protein recognition specificity of the dynlt1/tctex1 canonical binding groove. Characterization of the interaction with activin receptor iib

Structure:

Dynein light chain tctex-type 1,cytoplasmic dynein 1 intermediate chain 2. Chain: a, b. Fragment: unp residues 1-113,unp residues 134-154. Synonym: protein cw-1,t-complex testis-specific protein 1 homolog, cytoplasmic dynein intermediate chain 2,dynein intermediate chain 2, cytosolic,dh ic-2. Engineered: yes. Other_details: residues g1 to s2 correspond to the expression tag.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: dynlt1, tctel1, tctex-1, tctex1, dync1i2, dnci2, dncic2. Expressed in: escherichia coli. Expression_system_taxid: 562

NMR struc:

20 models

Authors:

I.Rodriguez-Crespo,J.Merino-Gracia,M.Bruix,H.Zamora-Carreras

Key ref:

J.Merino-Gracia et al. (2016). Molecular Basis for the Protein Recognition Specificity of the Dynein Light Chain DYNLT1/Tctex1: CHARACTERIZATION OF THE INTERACTION WITH ACTIVIN RECEPTOR IIB. J Biol Chem, 291, 20962-20975. PubMed id: 27502274 DOI: 10.1074/jbc.M116.736884

Date:

04-May-16 Release date: 17-Aug-16

Protein chains

P63172  (DYLT1_HUMAN) -  Dynein light chain Tctex-type 1 from Homo sapiens

Seq: 113 a.a.

Struc: 143 a.a.

Protein chains

Q13409  (DC1I2_HUMAN) -  Cytoplasmic dynein 1 intermediate chain 2 from Homo sapiens

Seq: 638 a.a.

Struc: 143 a.a.*

* PDB and UniProt seqs differ at 109 residue positions (black crosses)

DOI no: 10.1074/jbc.M116.736884

J Biol Chem 291:20962-20975 (2016)

PubMed id: 27502274

Molecular Basis for the Protein Recognition Specificity of the Dynein Light Chain DYNLT1/Tctex1: CHARACTERIZATION OF THE INTERACTION WITH ACTIVIN RECEPTOR IIB.

J.Merino-Gracia, H.Zamora-Carreras, M.Bruix, I.Rodríguez-Crespo.

ABSTRACT

No abstract given.