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PDBsum entry 5is7
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PDB id:
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Transferase
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Title:
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Crystal structure of mouse carm1 in complex with decarboxylated sah
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Structure:
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Histone-arginine methyltransferase carm1. Chain: a, b, c, d. Synonym: coactivator-associated arginine methyltransferase 1,protein arginine n-methyltransferase 4. Engineered: yes
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Source:
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Mus musculus. Mouse. Organism_taxid: 10090. Gene: carm1, prmt4. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108
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Resolution:
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2.29Å
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R-factor:
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0.211
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R-free:
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0.247
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Authors:
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V.Cura,N.Marechal,J.Mailliot,N.Troffer-Charlier,P.Hassenboehler, J.M.Wurtz,L.Bonnefond,J.Cavarelli
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Key ref:
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V.Cura
et al.
Crystal structure of mouse carm1 in complex with decarboxylated sah.
To be published,
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Date:
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15-Mar-16
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Release date:
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15-Mar-17
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PROCHECK
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Headers
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References
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Q9WVG6
(CARM1_MOUSE) -
Histone-arginine methyltransferase CARM1 from Mus musculus
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Seq:
Struc:
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608 a.a.
343 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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Enzyme class:
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E.C.2.1.1.319
- type I protein arginine methyltransferase.
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Reaction:
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L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)- dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H+
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L-arginyl-[protein]
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+
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2
×
S-adenosyl-L-methionine
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=
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N(omega),N(omega)- dimethyl-L-arginyl-[protein]
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+
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2
×
S-adenosyl-L-homocysteine
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+
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2
×
H(+)
Bound ligand (Het Group name = )
matches with 88.46% similarity
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
