PDBsum entry 5dv8

Transcription/transferase

PDB id: 5dv8

Contents

Protein chain

269 a.a.

Ligands

HIS-LYS-ILE-LEU-HIS-ARG-LEU-LEU-GLN-GLU

T51

Waters ×39

PDB id:

5dv8

Name:

Transcription/transferase

Title:

Human ppargamma ligand binding dmain complexed with sb1451 in a covalent bonded form

Structure:

Peroxisome proliferator-activated receptor gamma. Chain: a. Fragment: unp residues 223-505. Synonym: ppar-gamma,nuclear receptor subfamily 1 group c member 3. Engineered: yes. Nuclear receptor coactivator 1. Chain: b. Fragment: unp residues 685-700. Synonym: ncoa-1,class e basic helix-loop-helix protein 74,bhlhe74,

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: pparg, nr1c3. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606

Resolution:

2.75Å R-factor: 0.194 R-free: 0.243

Authors:

J.Y.Jang

Key ref:

J.Y.Jang Human ppargamma ligand binding dmain complexed with s in a covalent bonded form. To be published, .

Date:

21-Sep-15 Release date: 21-Sep-16

Protein chain

P37231  (PPARG_HUMAN) -  Peroxisome proliferator-activated receptor gamma from Homo sapiens

Seq: 505 a.a.

Struc: 269 a.a.

Enzyme reactions

• Enzyme class: E.C.2.3.1.48 - histone acetyltransferase.
• Reaction: L-lysyl-[protein] + acetyl-CoA = N₆-acetyl-L-lysyl-[protein] + CoA + H⁺

Molecule diagrams generated from .mol files obtained from the KEGG ftp site