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PDBsum entry 5ccs
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PDB id:
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Isomerase
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Title:
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Human cyclophilin d complexed with inhibitor
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Structure:
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Peptidyl-prolyl cis-trans isomerase f, mitochondrial. Chain: x. Fragment: unp residues 44-207. Synonym: ppiase f,cyclophilin d,cypd,cyclophilin f,mitochondrial cyclophilin,cyp-m,rotamase f, human cyclophilin d. Engineered: yes. Mutation: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: ppif, cyp3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
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Resolution:
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2.10Å
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R-factor:
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0.162
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R-free:
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0.196
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Authors:
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R.P.Gibson,E.Shore,N.Kershaw,M.Awais,A.Javed,D.Latawiec, S.Pandalaneni,L.Wen,N.Berry,P.O'Neill,R.Sutton,L.Y.Lian
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Key ref:
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R.P.Gibson
et al.
Human cyclophilin d complexed with inhibitor.
To be published,
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Date:
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02-Jul-15
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Release date:
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20-Jul-16
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PROCHECK
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Headers
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References
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P30405
(PPIF_HUMAN) -
Peptidyl-prolyl cis-trans isomerase F, mitochondrial from Homo sapiens
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Seq:
Struc:
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207 a.a.
164 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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*
PDB and UniProt seqs differ
at 2 residue positions (black
crosses)
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Enzyme class:
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E.C.5.2.1.8
- peptidylprolyl isomerase.
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Reaction:
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[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)
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Peptidylproline (omega=180)
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=
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peptidylproline (omega=0)
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
